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Medical Offices of Manhattan
What are the side effects of antihistamines in older adults?

This second-generation antihistamine may have higher negative effects in elderly people. Second-generation antihistamines may produce weariness and drowsiness in this age range, which can lead to falls and injuries. Your metabolism slows with age, making you more sensitive to drugs.

Jared Braunstein, DO, an internist at the Medical Offices of Manhattan in New York, advises older people with cardiovascular disease, urinary retention, or glaucoma not to use antihistamines, even second-generation ones. Read the article.